Muzaffargarh is one of the main cities in the south-western part of Punjab province, and the capital city of Muzaffargarh district. City is located at the bank of Chenab River and is very rich in agriculture and forests, it is also one of the oldest civilizations in South Asia, which was ruled by several emperors like Kambojas, the Daradas, the Kekayas, the Madras, the Pauravas, the Yaudheyas, the Malavas and the Kurus are the most famous civilizations who lived in this region. Weather conditions in city of Muzaffargarh are very extreme like its neighboring city of Multan, extreme hot and long summer and cold dry winters. According to the census of 2017 total population of city of Muzaffargarh is 1,621,744. Official postal code for city of Muzaffargarh is 34200, and dialing code is 066.

City is connected with all the major cities of Pakistan through the branch railway line that connects Rawalpindi, Multan, Mianwali, & Attock. And the Main Line that runs from Karachi to Peshawar goes through Multan which is closest main city in this area. Muzaffargarh has an air strip which is not open for public and only used for special VIP purposes & for military usage, this air strip is located in Mehmud Kot a suburban area of Muzaffargarh city. Closest international airport from here is Multan.

Major industries in the area is Pak Arab refinery which produce more than 35% of Pakistan’s refining capacity, KAPCO which is Kot Addu Power company is also located in this region with other mega power generation projects like PARCO Oil refinery, Lal Pir Power Plant, Thermal Power Station of Muzaffargarh, and the most famous is Muzaffargarh Nuclear Power Complex.